| 1 | 4 Nov 2022 | 18:30 | 1 Urbana 48 - 0 8 Tuscarora | |
| 2 | 3 Nov 2022 | 18:00 | 4 Reservoir 21 - 29 5 Mount Hebron | |
| 3 | 4 Nov 2022 | 18:30 | 3 Seneca Valley 43 - 7 6 Thomas Johnson | |
| 4 | 4 Nov 2022 | 19:00 | 2 Howard 28 - 0 7 Watkins Mill | |
| 5 | 4 Nov 2022 | TBA | 1 Dundalk vs BYE | |
| 6 | 4 Nov 2022 | 17:00 | 4 Kenwood 24 - 36 5 Dulaney | |
| 7 | 4 Nov 2022 | 18:00 | 3 Mervo 72 - 17 6 Catonsville | |
| 8 | 4 Nov 2022 | 17:30 | 2 Perry Hall 25 - 0 7 Woodlawn | |
| 9 | 3 Nov 2022 | 18:30 | 1 Sherwood 42 - 0 8 Northwood | |
| 10 | 3 Nov 2022 | 18:30 | 4 Kennedy 6 - 34 5 Springbrook | |
| 11 | 3 Nov 2022 | 18:30 | 3 Magruder 7 - 13 6 Wootton | |
| 12 | 3 Nov 2022 | 18:30 | 2 Blake 47 - 14 7 Whitman | |
| 13 | 4 Nov 2022 | TBA | 1 Arundel vs BYE | |
| 14 | 4 Nov 2022 | 18:30 | 4 Leonardtown 28 - 9 5 South River | |
| 15 | 4 Nov 2022 | 18:30 | 3 Severna Park 13 - 19 6 Chopticon | |
| 16 | 4 Nov 2022 | 19:00 | 2 North Point 50 - 0 7 Great Mills | |
| 17 | 12 Nov 2022 | 17:30 | 1 Urbana 42 - 7 5 Mount Hebron | |
| 18 | 11 Nov 2022 | 18:30 | 3 Seneca Valley 40 - 0 2 Howard | |
| 19 | 11 Nov 2022 | 19:00 | 1 Dundalk 34 - 0 5 Dulaney | |
| 20 | 11 Nov 2022 | 18:00 | 3 Mervo 6 - 7 2 Perry Hall | |
| 21 | 11 Nov 2022 | 18:30 | 1 Sherwood 55 - 14 5 Springbrook | |
| 22 | 11 Nov 2022 | 18:30 | 6 Wootton 8 - 27 2 Blake | |
| 23 | 11 Nov 2022 | 19:00 | 1 Arundel 29 - 3 4 Leonardtown | |
| 24 | 11 Nov 2022 | 19:00 | 6 Chopticon 0 - 35 2 North Point | |
| 25 | 18 Nov 2022 | 18:30 | 1 Urbana 30 - 6 8 Perry Hall | |
| 26 | 18 Nov 2022 | 18:30 | 4 Sherwood 0 - 31 5 North Point | |
| 27 | 18 Nov 2022 | 19:00 | 3 Arundel 21 - 7 6 Seneca Valley | |
| 28 | 18 Nov 2022 | 19:00 | 2 Dundalk 37 - 0 7 Blake | |
| 29 | 25 Nov 2022 | 18:30 | 1 Urbana 0 - 17 5 North Point | |
| 30 | 25 Nov 2022 | 19:00 | 3 Arundel 6 - 0 2 Dundalk | |
| 31 | 2 Dec 2022 | 19:30 | 5 North Point 31 - 14 3 Arundel | |